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Fig. 2 | Fluids and Barriers of the CNS

Fig. 2

From: Increased age and male sex are independently associated with higher frequency of blood–cerebrospinal fluid barrier dysfunction using the albumin quotient

Fig. 2

Correlations between age and albumin levels in cerebrospinal fluid (CSF) and serum. Serum albumin levels decreased with age in all patients analysed as a whole (Spearman: p < 0.0001) and grouped by sex (Spearman: p < 0.0001 for woman and p < 0.0001 for men). CSF albumin levels increased with age in the entire population (Spearman: p < 0.0001) and in the female subgroup (Spearman: p < 0.0001). The CSF/serum albumin ratio (QAlb) increased with age in all patients analysed as a whole (Spearman: p < 0.0001) and grouped by sex (Spearman: p < 0.0001 in women and p = 0.0191 in men). CI confidence interval

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