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Fig. 7 | Fluids and Barriers of the CNS

Fig. 7

From: Effects of aging on hydrocephalus after intraventricular hemorrhage

Fig. 7

a Examples of T2-weighted MRIs 24 h after intraventricular injection of FeCl3 in young (3 months) and aged (18 months) rats. Note the bigger dilated ventricles in the aged rats. Ventricular volumes were quantified (bar graph). Values are mean ± SD; n = 7, *p < 0.05 vs. aged rats group by Student t test. b Iba-1 immunoreactivity in the choroid plexus 24 h after intraventricular injection of FeCl3 in young and aged rats. The number of Iba-1 positive cells was calculated and expressed relative to the number of choroid plexus epithelial cells. Values are mean ± SD; n = 7, *p < 0.05 vs. aged rats group by Student t test. Scale bar = 100 µm (upper and middle row) and 20 µm (lower row). (C) CD68 immunoreactivity in the choroid plexus 24 h after intraventricular injection of FeCl3 in young and aged rats. The number of Iba-1 positive cells was calculated and expressed relative to the number of choroid plexus epithelial cells. Values are mean ± SD; n = 7, *p < 0.05 vs. aged rats group by Student t test. Scale bar = 100 µm (upper and middle row) and 20 µm (lower row)

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