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Table 5 TMS responses and motor parameters before and after lumbar puncture

From: Corticospinal excitability in idiopathic normal pressure hydrocephalus: a transcranial magnetic stimulation study

 

Pre-LP mean ± SD

Post-LP mean ± SD

p-value

Upper limb SP (ms)

55.5 ± 17.4

54.1 ± 20.1

0.227

Upper limb RMT (%-MSO)

26.4 ± 4.3

26.1 ± 3.9

0.462

Upper limb EF (V/m)

82.1 ± 13.0

83.9 ± 16.0

0.601

Lower limb RMT (%-MSO)

42.2 ± 7.6

43.1 ± 8.3

0.146

Lower limb EF (V/m)

149.3 ± 44.2

139.2 ± 34.8

0.586

IO-max (mV)

4.8 ± 2.7

4.9 ± 2.8

0.959

IO-50 (%)

35.8 ± 5.7

36.4 ± 4.9

0.642

IO-slope

2.6 ± 1.2

3.1 ± 1.4

0.049*

TSG (score)

53.7 ± 25.0

58.0 ± 25.2

0.039*

Gait velocity (m/s)

0.86 ± 0.27

0.95 ± 0.25

0.002*

Steps (number)

23.1 ± 6.7

21.7 ± 4.9

0.017*

BBT (pcs)

54.5 ± 12.5

54.6 ± 10.2

0.634

GPT (s)

142.3 ± 105.2

125.2 ± 54.0

0.705

Balance (score)

62.5 ± 12.4

66.1 ± 4.0

0.141

  1. n = 18
  2. SP silent period, RMT resting motor threshold, EF electric field, IO-max the maximum value of the input–output curve, IO-50 the mid-point of the input–output curve, IO-slope the slope of the input–output curve, TSG total score of gait, BBT Box and Block Test, GPT Grooved Pegboard Test, Pre-LP before lumbar puncture, Post-LP after lumbar puncture
  3. * Significant differences (p < 0.05) have been indicated (Wilcoxon signed-rank test)