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Fig. 6 | Fluids and Barriers of the CNS

Fig. 6

From: In Xenopus ependymal cilia drive embryonic CSF circulation and brain development independently of cardiac pulsatile forces

Fig. 6

Xenopus tropicalis ventricular cilia distribution in brain explants (Stage 46). a Mid-sagittal OCT image showing flow fields 4 and 5. a1 Brain stained with an anti-GT335 antibody (red) which labels cilia, and with phalloidin (green) which labels actin to mark cell borders. The dorsal fourth ventricle roof is populated with MCCs that display translational polarity. a2 The lateral walls of the 4th ventricle displays monociliated cells. a3 The ventral surface of the 4th ventricle populated with monociliated cells. b The lateral, third, and midbrain ventricles show a dense population of monociliated cells. Lat-v: lateral ventricle, III: 3rd ventricle, M: midbrain ventricle, IV: 4th ventricle, CA: cerebral aqueduct, FF: flow field

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