Fig. 3
From: Cerebrospinal fluid drainage kinetics across the cribriform plate are reduced with aging
Albumin tissue distribution at CSF outflow regions. Representative images of Albumin-Alexa Fluor-488 in frozen sections show no significant parenchyma distribution at 150 min (a) or at 30 min (b). Each section is 500 μm apart. c Representative images of Albumin-Alexa Fluor-488 distribution for the spinal column (cervical, thoracic and lumbar regions) at 150 min. d Prox1Tom expression (lymphatic vessels) in the superficial cervical lymph node, (red), Albumin-Alexa Fluor-488 distribution (green) and merged images at 30 min showing no significant levels of the tracer. e Images of the dura showing Prox1Tom expression (red), Albumin-Alexa Fluor-488 distribution (green) and merged images at 30 min. There is no significant levels of the tracer associated with Prox1 Tom (lymphatic vessels). N = 3 young male mice. Scale bar: 5 mm