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Fig. 4 | Fluids and Barriers of the CNS

Fig. 4

From: LC–MS/MS-based in vitro and in vivo investigation of blood–brain barrier integrity by simultaneous quantitation of mannitol and sucrose

Fig. 4

a, c Differences in brain concentration and brain uptake clearance (Kin) of [13C6]mannitol with or without correction by vascular marker. b, d Cbr and Kin of [13C12]sucrose with or without correction by vascular marker. ***p < 0.001 (n = 6), analyzed by Student’s paired t-test (two-tailed). N.S. Student’s unpaired t-test

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Fluids and Barriers of the CNS

ISSN: 2045-8118