Table 5 Cerebrospinal fluid (CSF) basic parameters
|  | Reference | All patient (N = 989) | Females (N = 545; 55%) | Males (N = 444; 45%) | Statistics | |
|---|---|---|---|---|---|---|
Cerebrospinal fluid (CSF) basic parameters | ||||||
 CSF protein concentration (Mean ± SD, range) |  | 470.91 ± 236.45 (from 107 to 2890 mg/l) | 423.74 ± 196.84 | 528.70 ± 266.44 | F = 60.366 p < 0.001 | |
 Increased CSF protein concentration |  < 450 mg/l | ↑: 447 (45%)  ↔ : 541 (55%) n.a.: 1 (0.1%) | ↑: 202 (37%)  ↔ : 342 (63%) n.a.: 1 (0.2%) | ↑: 245 (55%)  ↔ : 199 (45%) n.a.: 0 (0%) | β = 0.859 Wald = 39.542 p < 0.001 | |
 WBC counts (Mean ± SD) |  | 1.96 ± 4.85 (from 1 to 101 /µl) | 1.99 ± 5.33 | 1.93 ± 4.20 | F = 0.070 p = 0.791 | |
 Increased WBC counts |  < 5 /µl | ↑: 37 (4%)  ↔ : 942 (96%) n.a.: 1 (0.1%) | ↑: 25 (5%)  ↔ : 511 (95%) n.a.: 9 (2%) | ↑: 12 (3%)  ↔ : 431 (97%) n.a.: 1 (0.2%) | Wald = 2.777 p = 0.096 | |
 IgG-Index (Mean ± SD) |  | 0.50 ± 0.10 | 0.50 ± 0.11 | 0.50 ± 0.09 | F = 0.508 p = 0.476 | |
 Increased IgG indices |  | ↑: 19 (2%)  ↔ : 970 (98%) | ↑: 14 (3%)  ↔ : 531 (97%) | ↑: 5 (1%)  ↔ : 439 (99%) | Wald = 2.367 p = 0.124 | |
Isolated OCB in CSF OCBs in CSF and Serum | negative negative | 40 (4%) n.a.: 24 (2%) 52 (5%) n.a.: 25 (3%) | 21 (4%) n.a.: 16 (3%) 27 (5%) n.a.: 16 (3%) | 19 (4%) n.a.: 8 (2%) 25 (6%) n.a.: 9 (2%) | Wald = 0.095 p = 0.758 Wald = 0.456 p = 0.500 | |
Inflammatory CSF changesa |  | 77 / 989 (8%) | 48 / 545 (9%) | 29 /444 (7%) | Wald = 1.754 p = 0.185 | |
Overall Basic CSF changesb |  | 491 / 989 (50%) | 232 / 545 (43%) | 259 / 444 (58%) | β = 0.747 Wald = 30.608 p < 0.001 | |