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Fig. 5 | Fluids and Barriers of the CNS

Fig. 5

From: The microvascular extracellular matrix in brains with Alzheimer’s disease neuropathologic change (ADNC) and cerebral amyloid angiopathy (CAA)

Fig. 5

Differential content of laminin, TSG-6, and HA in MV isolated from no CAA and moderate to severe CAA brains. Western immunoblot assays showed that expression of laminin (a, inset of representative western blot) was significantly lower in lysates of MV isolated from no CAA brains vs. moderate-severe (Mod-Sev) CAA brains). Analyses of TSG-6 (b, inset of representative western blot) and HA (ELISA) content showed significant increases with moderate to severe CAA. Shown are scatter plots with mean and SEM, p values are as shown. Sample sizes (n) are indicated in “Results”

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Fluids and Barriers of the CNS

ISSN: 2045-8118