Fig. 1

Density and diameter of MV are not significantly different in samples of parietal cortex from not, intermediate, and high ADNC subjects. Density (a) and diameter (b) of MV (identified by IF for alpha-smooth muscle actin as shown in insets of representative images in both a and b) in sections of parietal cortex in not ADNC, intermediate (Int) ADNC, and high ADNC. c MV density assays similar to those in a, but identifying MV by chromogenic IHC for endothelial cell PECAM (c, scatter plot with mean and SEM; inset, representative image) and vWF (d, scatter plot with mean and SEM; inset, representative image). These assays show no significant differences in MV density and diameter among the three groups. Inset scale bars are 20 µm (a, c, d) and 10 µm (b). Sample sizes (n) are indicated in “Results”