Diabetes is associated with familial idiopathic normal pressure hydrocephalus: a case–control comparison with family members

Table 4 Logistic regression analysis comparing the probable fNPH patients (n = 60) and their non-iNPH relatives, age ≥ 60 (n = 49) as a reference category

Clinical variable	n	Model	OR	95% CI	p-value
Age at questionnaire	109	Univariate	1.121	1.057–1.189	< 0.001
Age at questionnaire	107	Multivariate	1.123	1.061–1.189	< 0.001
Diabetes	109	Univariate	2.780	1.057–7.317	0.038
Diabetes	107	Multivariate	3.840	1.142–12.912	0.030
Cardiac insufficiency	107	Univariate	8.816	1.075–72.282	0.043
Cardiac insufficiency	107	Multivariate	4.250	0.475–38.030	0.196
Arterial hypertension	109	Univariate	2.476	1.140–5.378	0.022
Arterial hypertension	107	Multivariate	1.147	0.444–2.959	0.777

Italic values indicate significance of p value (< 0.05)
Hosmer–Lemeshow = 0.189; Overall percentage = 75.7%
fNPH familial idiopathic normal pressure hydrocephalus, OR odds ratio, CI confidence interval

ISSN: 2045-8118