Table 1 Parameters used in simulations

Arteriolar radius

R₁

12

5 to 20

µm

[49,50,– 51]

PVS length

L_a

250

250 to 500

µm

[50, 145]

PVS width

wd

3

2–10

µm

[16, 42, 43]

CSF viscosity

µ_f

0.001

–

Pa.s

[47, 48]

CSF density

ρ_f

1000

-

kg/m³

[47, 48]

PVS porosity

ζ

0.8

0.5–0.9

–

[16, 17, 146]

PVS permeability

k_s

2 × 10⁻¹⁴

7 × 10⁻¹³ to 2 × 10⁻¹⁵

m²

[12, 14, 45, 46]

Brain section radius

R₃

150

100–200

µm

[145, 147]

Brain shear modulus

µ_s

4

1–8

kPa

[29,30,31,32, 63,64,65,66]

Brain tissue density

ρ₁

1000

–

kg/m³

[148]

Pulsation amplitude (% arteriolar radius)

b₁

1

0.5–2

–

[16]

Pulsation frequency

f

10

7–14

Hz

[72]

Pulse wave speed

c

1

0.5–10

m/s

[69,70,71]

Pulse wave wavelength

λ

0.1

0.03–1.43

m

c/f

Diffusion coefficient

D

1.4 × 10⁻⁶

–

cm²/s

[134, 135]