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Table 1 Comparison of transendothelial electrical resistance (TEER) in hCMEC/D3-WT vs. hCMEC/D3-Cldn5-YFP cells

From: A face-to-face comparison of claudin-5 transduced human brain endothelial (hCMEC/D3) cells with porcine brain endothelial cells as blood–brain barrier models for drug transport studies

Day after seeding TEER (Ω cm2)
hCMEC/D3-WT hCMEC/D3-Cldn5-YFP
1 10.1 ± 0.8 15.2 ± 1.2*
2 14.8 ± 0.8 22.6 ± 0.8*
3 18.7 ± 0 26.5 ± 1.5*
4 19.5 ± 0.8 26.5 ± 1.5*
5 18.7 ± 0 26.5 ± 1.5*
6 16.3 ± 2.3 24.9 ± 1.5*
7 15.5 ± 1.5 26.5 ± 1.5*
8 16.3 ± 2.3 28.0 ± 0*
9 17.9 ± 2.1 26.5 ± 1.5*
  1. Data are presented as the mean ± SEM of 3 replicates. TEER was measured utilizing an EndOhm-6 tissue resistance measurement chamber. Significant difference between hCMEC/D3-WT and hCMEC/D3-Cldn5-YFP cells is indicated by asterisk (P < 0.05). This experiment is a repeat of the experiment shown in Fig. 4b, but TEER measurements were performed up to 9 days after seeding