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Table 1 Summary of different clusters of gene responses

From: Contribution of brain pericytes in blood–brain barrier formation and maintenance: a transcriptomic study of cocultured human endothelial cells derived from hematopoietic stem cells

 

Differentially expressed

Down-regulated

Up-regulated

Total regulated

Down-regulated

Up-regulated

Total regulated

%

(p-value < 0.05; |log2FC| | > 1)

(p-value < 0.05; |log2FC| > 2)

CBP vs. Solo (h)

 24

5.8

207

114

321 (1.2%)

49

26

75 (0.3%)

 48

14.6

302

343

645 (2.5%)

70

109

179 (0.7%)

 96

15.1

513

253

766 (3.0%)

148

72

210 (0.8%)

CHP vs. SOLO (h)

 24

20.4

414

534

948 (3.7%)

41

199

240 (0.9%)

 48

16.1

297

561

858 (3.3%)

54

188

242 (0.9%)

 96

18.7

644

591

1235 (4.8%)

114

260

374 (1.5%)

  1. The percentage of differentially expressed transcripts (p < 0.05) is shown in the second column for every condition and is depicted as a percentage of the total number (i.e. 25 684) of mapped genes. Column 3 and 4 show differentially expressed transcripts in cocultured vs. solocultured endothelial cells characterized by a |log2FC| > 1. Column 6 and 7 depict differentially expressed transcripts characterized by a |log2FC| > 2