Fig. 1From: Location matters: highly divergent protein levels in samples from different CNS compartments in a clinical trial of rituximab for progressive MSDesign of the studies displaying treatments given and sample collections used in this paper. The bar shows the transition from the Intrathecal Treatment Trial in Progressive Multiple Sclerosis (ITT-PMS) to the follow-up extension study, with time shown below in months. Black arrows display points of treatment. Scalpel indicates implantation of Ommaya reservoir and collection of ventricular CSF during surgery, and test tubes indicate collection of paired lumbar and ventricular CSF. MD, microdialysis; n, number of participantsBack to article page