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Fig. 3 | Fluids and Barriers of the CNS

Fig. 3

From: Modeling blood–brain barrier pathology in cerebrovascular disease in vitro: current and future paradigms

Fig. 3

Current models of blood–brain barrier (BBB)/neurovascular unit (NVU) in vitro. The flowchart summarizes the advantages and disadvantages of the current 2-D and 3-D models of BBB/NVU. BEC, brain endothelial cell; iPSC, induced pluripotent stem cell, DIV-BBB, dynamic in vitro BBB model; μBBB, microfluidic-based BBB; SyM-BBB, synthetic microvascular model of BBB

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