Fig. 4

ICP waveform features: Continuous ICP monitoring in rats. a Representative ICP trace of a rat during its recovery period during the active phase (dark phase), inserted pressure represents mean ICP for the period shown. b Trace detailing ICP waveform features, where B-like ICP waves are highlighted. c Bar graph comparing the number of ICP spikes observed in a 3 h window in the RP and PP. d Representative ICP trace of a rat in the physiological period during its active phase, inserted pressure represents mean ICP for the period shown. e Trace detailing waveform features, where ICP spikes are highlighted with arrows. All traces show 1 s ICP mean values. C presented as mean ± SEM, where data analyzed by paired T-test where N = 10. **P < 0.01