Table 1 Clinical and experimental characteristics of DIPG cells
Cells | WHO grade | Histology | Age at diagnosis (years) | Sex | Tissue origin | ACVR1 mutation | H3F3A mutation |
|---|---|---|---|---|---|---|---|
HSJD-DIPG-007 | IV | Glioblastoma multiforme | 9.9 | M | Autopsy | Mutated | p.Lys27Met or K27M |
HSJD-DIPG-013 | IV | Anaplastic astrocytoma | 6.0 | F | Biopsy | WT | p.Lys27Met or K27M |
HSJD-DIPG-014 | IV | Anaplastic astrocytoma | 8.2 | F | Biopsy | WT | p.Lys27Met or K27M |