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Fig. 5 | Fluids and Barriers of the CNS

Fig. 5

From: Development of a human in vitro blood–brain tumor barrier model of diffuse intrinsic pontine glioma to better understand the chemoresistance

Fig. 5

Detoxification enzymes expression in the BBB and the BBTB models. Transcriptional expression of the genes of cytochrome P450 enzymes CYP1A1, CYP1B1, CYP2D6, CYP2S1 and CYP2U1, after 7 days of incubation, normalized on the expression of the housekeeping gene PPIA (cyclophilin A). ***p < 0.001; **p < 0.01; *p < 0.05. N = 3; n = 9

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Fluids and Barriers of the CNS

ISSN: 2045-8118