Fig. 5From: Development of a human in vitro blood–brain tumor barrier model of diffuse intrinsic pontine glioma to better understand the chemoresistanceDetoxification enzymes expression in the BBB and the BBTB models. Transcriptional expression of the genes of cytochrome P450 enzymes CYP1A1, CYP1B1, CYP2D6, CYP2S1 and CYP2U1, after 7 days of incubation, normalized on the expression of the housekeeping gene PPIA (cyclophilin A). ***p < 0.001; **p < 0.01; *p < 0.05. N = 3; n = 9Back to article page