Skip to main content
Fig. 2 | Fluids and Barriers of the CNS

Fig. 2

From: Choroid plexus and the blood–cerebrospinal fluid barrier in disease

Fig. 2

Schematic illustration of the molecular interactions of TJ proteins in CP epithelial cells. TJ proteins and their complex interactions with other proteins form the connections between adjacent epithelial cells in the B-CSF barrier. Claudin, occludins, and JAMs are linked to actin filaments through ZO proteins. Cingulin, another cytoplasmic protein, is recruited to TJ through ZO. The interaction between TJ proteins and the cytoplasmic protein network is crucial for maintaining B-CSF barrier integrity (adapted from [72])

Back to article page