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Table 3 Effect of modifications to steady state results of the model on ICP and flow

From: Intracranial pressure elevation alters CSF clearance pathways

ModICP (\(p_0\)) [mmHg]AG flow [mL/min]PVS flow [mL/min]Crib flow [mL/min]Cap flow [mL/min]\(R_0\) [\(\frac{{\text {mmHg}}}{{\text {mL/min}}}\)]
011.66 (24.16)− 0.33 (− 1.83)n/an/an/a8.60
110.99 (24.28)− 0.24 (− 1.47)0.04 (0.00)− 0.16 (− 0.36)0.07 (0.00)8.67
28.98 (12.21)− 0.05 (− 0.35)− 0.14 (− 1.30)− 0.13 (− 0.18)0.09 (0.07)2.16
311.81 (25.77)− 0.31 (− 1.61)0.10 (0.10)− 0.18 (− 0.38)0.16 (0.16)9.31
410.32 (24.28)− 0.18 (− 1.47)n/a− 0.15 (− 0.36)n/a9.31
522.11 (122.61)n/a0.00 (0.00)− 0.33 (− 1.83)0.00 (0.00)67.00
612.71 (36.28)− 0.20 (− 1.29)0.03 (0.00)− 0.19 (− 0.54)0.06 (0.00)14.47
78.42 (8.43)0.00 (0.00)− 0.20 (− 1.70)− 0.13 (− 0.13)0.09 (0.09)0.00
  1. Results are reported as max/min where max is the value at plateau ICP (shown within parenthesis), while min is the value at baseline ICP. Negative values indicate flow out from the SAS and into the given compartment. For capillary flow, positive values indicate secretion of fluid from the capillaries