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Table 1 Model 1 default parameters (corresponding to full model) cf. Fig. 1 and Eqs. (1), (2)

From: Intracranial pressure elevation alters CSF clearance pathways

ParameterSymbolValueUnitReferences
Dural sinus pressure\(p_{{\text {d}}}\)8.4mmHgEq. (17 ) [61,62,63]
Cervical lymph pressure\(p_{{\text {crib}}}\)0mmHg[64]
Pial sleeves pressure\(p_{{\text {V}}}\)8.4mmHgModel assumption
Hydrostatic capillary pressure\(p_{cap,h}\)35mmHg[73]
Effective capillary pressure\(p_{\mathrm{cap}}\)20mmHgEq. (19)
Reference pressure\(p_{{\text {r}}}\)9mmHg[39]
Threshold pressure\(p_{{\text {thres}}}\)11mmHg[34]
AGs resistance\(R_{{\text {AG}}}\)10.81mmHg/(mL/min)[57]
Paraarterial resistance\(R_{{\text {aPVS}}}\)1.14mmHg/(mL/min)[11]
Arterial IEG resistance\(R_{\mathrm{IEG,a}}\)0.57mmHg/(mL/min)Eq. (15) [50]
Venous IEG resistance\(R_{\mathrm{IEG,v}}\)0.64mmHg/(mL/min)Eq. (15) [50]
ECS resistance\(R_{\mathrm{ECS}}\)0.57mmHg/(mL/min)Eqs.  (12, 13) [14, 49]
Capillary gaps resistance\(R_{{\text {gaps}}}\)32.24mmHg/(mL/min)Eq. (8) [45]
Paravenous resistance\(R_{{\text {v}}}\)\(1.75 \times 10^{-3}\)mmHg/(mL/min)[11]
Lumped model resistance\(R_{{\text {V}}}\)1.69mmHg/(mL/min)Eq. (3)
Cribriform plate resistance\(R_{{\text {crib}}}\)67mmHg/(mL/min)Eq. (3)
Capillary wall resistance\(R_{{\text {cap}}}\)125.31mmHg/(mL/min)Eq. (16)
Subarachnoid space elastanceE0.2\({\text {mL}}^{-1}\)[27]
CSF production rate\(Q_{{\text {prod}}}\)0.33mL/min[40,41,42,43]
Infusion rate\(Q_{{\text {inf}}}\)1.5mL/min[27]