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Fig. 1 | Fluids and Barriers of the CNS

Fig. 1

From: Laminin 221 fragment is suitable for the differentiation of human induced pluripotent stem cells into brain microvascular endothelial-like cells with robust barrier integrity

Fig. 1

Evaluation of TEER values in LN221F- and Matrigel-iBMELCs. a Scheme for the differentiation of iBMELCs. b Relative TEER values of 610B1-derived iBMELCs on day 10 on Matrigel, FBN, VTN-N, LN221F, LN411F, or LN511F. The relative TEER value of iBMELCs on Matrigel was defined as 1. Data are presented as the mean ± SD (n = 3; *p < 0.05, **p < 0.01; Tukey’s honestly significant difference test, Matrigel group vs. others). c Measurement of TEER values of LN221F- and Matrigel-iBMELCs derived from 610B1 and 648A1 over a long period (from day 9 to 18). Data are presented as the mean ± SD (n = 6; **p < 0.01; two-way repeated measures analysis of variance)

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