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Fig. 1 | Fluids and Barriers of the CNS

Fig. 1

From: Cerebrospinal fluid dynamics in non-acute post-traumatic ventriculomegaly

Fig. 1

Representative example of CSF dynamics in a patient under investigation for possible Post Traumatic Hydrocephalus. ICP (monitored via Ommaya reservoir in this case) increased briskly after start of infusion, with an Rout around 11–13 mmHg/min/ml. AMP at baseline ~ 1 mmHg, also reacted briskly to infusion until a plateau of 5.6 mmHg. RAP at baseline ~ 0.6, clearly increased to almost 1 after infusion of only a few ml, indicating exhaustion of compensatory reserve. CSFp: CSF pressure (access to the CSF space via LP). AMP: fundamental amplitude of ICP. RAP: compensatory reserve index (moving correlation coefficient between ICP and AMP)

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