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Fig. 5 | Fluids and Barriers of the CNS

Fig. 5

From: Simvastatin, edaravone and dexamethasone protect against kainate-induced brain endothelial cell damage

Fig. 5

The effect of kainate and protective compounds on cell viability of primary rat brain endothelial cells. Rat brain endothelial cells were treated with 100 µM kainate (KA) without or with simvastatin (SIM, 1 µM), edaravone (EDA, 1 µM) or dexamethasone (DXM, 1 µM) for 24 h. Control groups (C) received only culture medium. Mean ± SD, n = 4–8, ANOVA, Bonferroni test, ***p < 0.001 compared to the control group, #p < 0.05, ##p < 0.01, ###p < 0.001 compared to the kainate-treated group

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