Normal mitochondria
|
Number of normal mitochondria per astrocytic endfoot process (N)
|
18.4 ± 9.4
|
2.6 ± 3.6
|
P < 0.001
|
Area of normal mitochondria per endfoot processes (nm2)
|
132,672 ± 48,823
|
81,923 ± 82,860
|
ns
|
Fraction of normal mitochondria per endfoot process (%)
|
7.2 ± 3.0
|
5.3 ± 5.6
|
ns
|
Pathological mitochondria
|
Number of pathological mitochondria per astrocytic endfoot process (N)
|
0.4 ± 0.8
|
3.8 ± 2.5
|
P = 0.003
|
Area of pathological mitochondria per endfoot processes (nm2)
|
28,903 ± 49,387
|
146,356 ± 86,682
|
P = 0.03
|
Fraction of pathological mitochondria per endfoot process (%)
|
1.8 ± 3.1
|
10.8 ± 8.4
|
ns
|