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Table 3 Normal and pathological mitochondria in astrocytic endfoot processes of REF and iNPH subjects

From: Pathological mitochondria in neurons and perivascular astrocytic endfeet of idiopathic normal pressure hydrocephalus patients

 REFiNPHSignificance
Normal mitochondria
 Number of normal mitochondria per astrocytic endfoot process (N)18.4 ± 9.42.6 ± 3.6P < 0.001
 Area of normal mitochondria per endfoot processes (nm2)132,672 ± 48,82381,923 ± 82,860ns
 Fraction of normal mitochondria per endfoot process (%)7.2 ± 3.05.3 ± 5.6ns
Pathological mitochondria
 Number of pathological mitochondria per astrocytic endfoot process (N)0.4 ± 0.83.8 ± 2.5P = 0.003
 Area of pathological mitochondria per endfoot processes (nm2)28,903 ± 49,387146,356 ± 86,682P = 0.03
 Fraction of pathological mitochondria per endfoot process (%)1.8 ± 3.110.8 ± 8.4ns
  1. Data presented as mean ± standard deviation (std). Significant differences between continuous variables were determined by multivariate analysis