|
Presynaptic terminals
|
|
Normal mitochondria
|
|
Number of normal mitochondria per presynaptic terminal (N)
|
25.6 ± 16.1
|
11.3 ± 5.3
|
ns
|
|
Area of normal mitochondria per presynaptic terminal (nm2)
|
91,017 ± 32,840
|
108,668 ± 81,513
|
ns
|
|
Fraction of normal mitochondria per presynaptic terminal (%)
|
11.9 ± 4.7
|
13.5 ± 9.6
|
ns
|
|
Pathological mitochondria
| | | |
|
Number of pathological mitochondria per presynaptic terminal (N)
|
0.1 ± 0.3
|
4.9 ± 4.2
|
P = 0.05
|
|
Area of pathological mitochondria per presynaptic terminal (nm2)
|
59,537 ± 178,611
|
152,763 ± 149,111
|
ns
|
|
Fraction of pathological mitochondria per presynaptic terminal (%)
|
7.2 ± 21.5
|
15.7 ± 6.4
|
ns
|
|
Postsynaptic terminals
|
|
Normal mitochondria
|
|
Number of normal mitochondria per postsynaptic terminal (N)
|
6.1 ± 5.6
|
2.9 ± 2.7
|
ns
|
|
Area of normal mitochondria per postsynaptic terminal (nm2)
|
160,597 ± 83,189
|
101,246 ± 83,823
|
P = 0.02
|
|
Fraction of normal mitochondria per postsynaptic terminal (%)
|
26.8 ± 15.1
|
15.2 ± 12.4
|
ns
|
|
Pathological mitochondria
|
|
Number of pathological mitochondria per postsynaptic terminal (N)
|
0
|
3.1 ± 2.7
|
P = 0.02
|
|
Area of pathological mitochondria per postsynaptic terminal (nm2)
|
0
|
158,834 ± 109,688
|
P = 0.03
|
|
Fraction of pathological mitochondria per postsynaptic terminal (%)
|
0
|
33.0 ± 20.4
|
P = 0.02
|
