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Table 1 Normal, pathological and clustered mitochondria in neuronal soma of REF and iNPH subjects

From: Pathological mitochondria in neurons and perivascular astrocytic endfeet of idiopathic normal pressure hydrocephalus patients

 REFiNPHSignificance
Normal mitochondria
 Number of normal mitochondria per soma (N)50.8 ± 31.236.8 ± 27.6ns
 Area of normal mitochondria per soma (nm2)134,348 ± 28,130122,202 ± 71,967ns
 Fraction of normal mitochondria per soma (%)0.9 ± 0.30.6 ± 0.3P = 0.014
Pathological mitochondria
 Number of pathological mitochondria per soma (N)8.8 ± 11.250.9 ± 37.5P = 0.004
 Area of pathological mitochondria per soma (nm2)240,857 ± 85,877191,807 ± 77,411ns
 Fraction of pathological mitochondria per soma (%)0.86 ± 0.730.94 ± 0.49ns
Clustered mitochondria
 Number of clustered mitochondria per soma (N)0.6 ± 1.313.6 ± 12.0P = 0.007
 Area of clustered mitochondria per soma (nm2)535,546 ± 238.686977,784 ± 501,167P = 0.005
 Fraction of clustered mitochondria per soma (%)0.7 ± 1.54.7 ± 3.3P = 0.04
  1. Data presented as mean ± standard deviation (std). Significant differences between continuous variables were determined by multivariate analysis