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Table 1 Normal, pathological and clustered mitochondria in neuronal soma of REF and iNPH subjects

From: Pathological mitochondria in neurons and perivascular astrocytic endfeet of idiopathic normal pressure hydrocephalus patients

 

REF

iNPH

Significance

Normal mitochondria

 Number of normal mitochondria per soma (N)

50.8 ± 31.2

36.8 ± 27.6

ns

 Area of normal mitochondria per soma (nm2)

134,348 ± 28,130

122,202 ± 71,967

ns

 Fraction of normal mitochondria per soma (%)

0.9 ± 0.3

0.6 ± 0.3

P = 0.014

Pathological mitochondria

 Number of pathological mitochondria per soma (N)

8.8 ± 11.2

50.9 ± 37.5

P = 0.004

 Area of pathological mitochondria per soma (nm2)

240,857 ± 85,877

191,807 ± 77,411

ns

 Fraction of pathological mitochondria per soma (%)

0.86 ± 0.73

0.94 ± 0.49

ns

Clustered mitochondria

 Number of clustered mitochondria per soma (N)

0.6 ± 1.3

13.6 ± 12.0

P = 0.007

 Area of clustered mitochondria per soma (nm2)

535,546 ± 238.686

977,784 ± 501,167

P = 0.005

 Fraction of clustered mitochondria per soma (%)

0.7 ± 1.5

4.7 ± 3.3

P = 0.04

  1. Data presented as mean ± standard deviation (std). Significant differences between continuous variables were determined by multivariate analysis