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Fig. 2 | Fluids and Barriers of the CNS

Fig. 2

From: Region-specific blood–brain barrier transporter changes leads to increased sensitivity to amisulpride in Alzheimer’s disease

Fig. 2

The effect of self-inhibition (20 μM) on the accumulation of [3H]amisulpride (6.5 nM) was determined in hCMEC/D3 (a) and bEnd.3 (b) cell lines. Significant differences compared to control were observed—*p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001, ****p ≤ 0.0001. All data have been corrected for [14C]sucrose and are expressed as mean ± S.E.M, n = 3 to 7 plates with 6 replicates (wells) per timepoint per plate (5 time-points)

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