Fluids and Barriers of the CNS

Table 1 Demographics and clinical characteristics of PML patients

From: Tau-protein concentrations are not elevated in cerebrospinal fluid of patients with progressive multifocal leukoencephalopathy

Case	P1	P2	P3	P4	P5	P6	P7	P8	P9	P10
Age (years)	77	76	55	43	72	31	57	54	54	42
Sex (M = male F = female)	M	M	M	M	M	M	M	M	M	F
UID	BC	NHL	CLL	MS	LT	HIV	HIV	MM	HIV	MS
mRS after PML	2	4	5	3	2	2	3	2	3	4
JCPyV DNA (c/ml)	100.000	200.000	499	500	Neg. (brain biopsy)	1080	800	179	249	249
T-tau (pg/ml)	332	374	218	190	121	568	87	239	389	118
P-tau (pg/ml)	49	34	24	43	36	62	22	51	56	36

UID underlying immunodeficiency, mRS modified Rankin Scale, BC bronchial carcinoma, NHL non-Hodgkin lymphoma, CLL chronic lymphocytic leukemia, MS multiple sclerosis treated with natalizumab, LT liver transplant, MM multiple myeloma, HIV human immunodeficiency virus

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ISSN: 2045-8118

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