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Fig. 3 | Fluids and Barriers of the CNS

Fig. 3

From: A perfusion bioreactor-based 3D model of the subarachnoid space based on a meningeal tissue construct

Fig. 3

a Meningeal tissue constructs revealed immunopositivity for cell–cell interaction markers of gap-junctions (connexin 26 and 43) and weak immunopositivity for desmosomes (desmoplakin) comparable to human optic nerve meninges. b Immunohistochemistry to stain for extracellular matrix markers. Meningeal tissue constructs revealed immunopositivity for collagens (pro-collagen, collagen II and IV), laminin I and tenascin. “Blue” indicates structure of collagen scaffold; “Brown” indicates immunopositivity for respective antibody

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Fluids and Barriers of the CNS

ISSN: 2045-8118