Fig. 3

Ratio of vesicular structures. a The amount of vesicles per cell is shown normalised to the number of early endosomes. b The amount of endosomes per cell is presented relative to the number of lysosomes. All values are presented as mean ± SEM, n > 9. Statistical analysis; Difference was analysed by one-way ANOVA followed by Tukey’s posthoc test. Values were considered statistically significant at *p ≤ 0.05, **p ≤ 0.01 between the cell lines (bEnd.3 vs. hCMEC/D3) and at ^#p ≤ 0.05, ^##p ≤ 0.01, ^###p ≤ 0.001 compared to the primary PBEC