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Fig. 4 | Fluids and Barriers of the CNS

Fig. 4

From: The need for mathematical modelling of spatial drug distribution within the brain

Fig. 4

The properties of a drug affecting its distribution within the brain. The molecular properties are the properties inherent to the drug and affect both its physicochemical and biochemical properties. The physicochemical properties describe the interaction of a drug with its physical environment, while the biochemical properties describe the binding affinities of a drug to other molecules. The pharmacokinetic properties depend on both the physicochemical and biochemical properties

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