Fig. 6

Microscopic distribution of CSF tracer in spinal cord white and gray matter 6 weeks post-surgery. Graphs illustrate mean fluorescence intensity measured microscopically in each spinal segment in the white matter (a, c) and gray matter (b, d) from control (n = 3 per group) and extradural constriction (10 min: n = 5; 20 min: n = 6) animals, 10 min (a, b) and 20 min (c, d) after cisterna magna injection of CSF tracer (OA-647). Results are shown as mean fluorescence ± SEM, given as arbitrary units (AU). Statistical significance was determined using two-way ANOVA, with Bonferroni’s multiple comparison test ****p < 0.0001, ***p < 0.001, **p < 0.01, *p < 0.05. WM: white matter; GM: gray matter