Opposing CSF hydrodynamic trends found in the cerebral aqueduct and prepontine cistern following shunt treatment in patients with normal pressure hydrocephalus

Table 3 p-value from the Mann–Whitney Rank sum comparing pre-treatment NPH and control patients for prepontine cistern peak flow latency

	Percentage of low-correlated voxels removed from the ROI
Degree of fit	1%	10%	25%	50%	75%	90%	95%
No poly fit	0.076	0.076	0.061	0.107	0.040	0.094	0.061
4	0.007	0.009	0.009	0.009	0.009	0.007	0.004
5	0.009	0.009	0.011	0.009	0.011	0.007	0.015
6	0.009	0.007	0.009	0.009	0.009*	0.007	0.015
7	0.023	0.014	0.014	0.025	0.023	0.009	0.036
8	0.044	0.036	0.044	0.044	0.029	0.009	0.067
9	0.036	0.036	0.044	0.040	0.029	0.011	0.067
10	0.066	0.055	0.036	0.044	0.036	0.011	0.116

For the analysis a six degree polynomial was used to fit the flow data and the top 25% of the voxels were used in the calculation (represents 75% of the low-correlated voxels being removed) p value shown with an *.The “No Poly Fit” row contains the results excluding any polynomial fitting

ISSN: 2045-8118