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Table 3 Unchanged genes with possible tendency of downregulation in AD CP

From: Choroid plexus genes for CSF production and brain homeostasis are altered in Alzheimer’s disease

Gene symbol Gene name p-value t-value (control relative to AD) Log2 fold change
SLC family
 SLC12A4 Solute carrier family 12 member 4: KCC1 K–Cl cotransporter 0.0947 1.78492648 0.23569524
 SLC4A2 Solute carrier family 4 member 2: Cl–HCO3 exchanger 0.130 1.60190388 0.21841905
 SLC38A3 Solute carrier family 38 member 3; system N amino acid transporter 0.223 1.27232445 0.2807
Na–K ATPase family
 ATP1B2 Na–K ATPase transporting subunit beta 2 0.0533 2.09928405 0.39634524
 ATP1A4 Na–K ATPase transporting subunit alpha 4 0.684 0.41463513 0.06897143
Carbonic anhydrase family
 CA8 Carbonic anhydrase 8 0.138 1.56854024 0.50962619
 CA14 Carbonic anhydrase 14 0.172 1.4334038 0.29066667
Tight junction claudins and occludin
 CLDN1 Claudin-1 0.188 1.37904737 0.35589048
 CLDN2 Claudin-2 0.161 1.47424712 0.43342857
 CLDN3 Claudin-3 0.0942 1.78793258 0.41007381
 CLDN19 Claudin-19 0.375 0.91449198 0.32223095
 OCLN Occludin 0.799 0.25905032 0.03019762
Others
 AQP4 Aquaporin 4 0.621 0.50457389 0.18047619
  1. Positive t values for comparisons represent gene changes decreased in AD relative to control (i.e. increased in control relative to AD). The same is true for positive log2FC values