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Table 2 Genes upregulated in AD  CP

From: Choroid plexus genes for CSF production and brain homeostasis are altered in Alzheimer’s disease

Gene symbol Gene name p-value t-value (control relative to AD) Log2 fold change
SLC family
 SLC25A37 Solute carrier family 25 member 37: mitochondrial iron transporter 0.000128 − 5.12740967 − 0.64122381
 SLC25A28 Solute carrier family 25 member 28; mitochondrial iron transporter 0.0000927 − 5.29698098 − 0.64098333
 SLCO4A1 Solute carrier organic anion transporter family member 4A1; organic anion transporter 0.000103 − 5.24167279 − 1.85499048
 SLC12A7 Solute carrier family 12 member 7; KCC4 K–Cl cotransporter 0.000741 − 4.23121588 − 0.67435
 SLC12A6 Solute carrier family 12 member 6; KCC3 K–Cl cotransporter 0.0262 − 2.46864419 − 0.52261429
Interleukin-1-receptor family
 IL1R1 Interleukin-1 receptor 0.0185 − 2.64459755 − 0.62269524
 IL1RL1 Interleukin 1 receptor-like 1 0.0000113 − 6.45879688 − 3.43624762
Carbonic anhydrase family
 CA13 Carbonic anhydrase 13 0.0152 − 2.74368279 − 0.51382619
Na–K ATPase family
 ATP1A1 Na–K ATPase transporting subunit alpha 1 0.0198 − 2.61012511 − 0.45077857
Amyloid proteins
 ABPA3 Amyloid beta precursor protein (APP) binding family A member 3 0.00154 − 3.86960931 − 0.51001667
 APBB1IP APP binding family B member 1 interacting protein 0.0116 − 2.87838249 − 0.53602143
  1. Negative t values are for comparisons displaying gene changes that are increased in AD relative to control (i.e. decreased in control relative to AD). The same is true for negative log2FC values