From: Choroid plexus genes for CSF production and brain homeostasis are altered in Alzheimer’s disease
Gene symbol | Gene name | p-value | t-value (control relative to AD) | Log2 fold change |
---|---|---|---|---|
SLC family | ||||
SLC26A2 | Solute carrier family 26 member 2; sulfate transporter | 0.0000313 | 5.88360095 | 1.43830952 |
SLC5A5 | Solute carrier family 5 member 5; sodium/iodine cotransporter | 0.0000375 | 5.78520397 | 0.75760238 |
SLC4A10 | Solute carrier family 4 member 10: Na-dependent Cl–HCO3 exchanger | 0.0275 | 2.44489236 | 0.39339524 |
SLC4A5 | Solute carrier family 4 member 5: Na–HCO3 exchanger | 0.00366 | 3.44425553 | 1.1215619 |
SLC12A1 | Solute carrier family 12 member 1: NKCC2 Na–K–Cl cotransporter | 0.0353 | 2.31563648 | 1.05009524 |
SLC12A2 | Solute carrier family 12 member 2: NKCC1 Na–K–Cl cotransporter | 0.00517 | 3.27527462 | 0.38004286 |
Na–K ATPase family | ||||
ATP1A2 | Na–K ATPase transporting subunit alpha 2 | 0.0387 | 2.26741686 | 0.50910238 |
ATP1B1 | Na–K ATPase transporting subunit beta 1 | 0.0429 | 2.21376353 | 0.29179286 |
Carbonic anhydrase family | ||||
CA4 | Carbonic anhydrase 4 | 0.000139 | 5.08319761 | 0.63055238 |
CA2 | Carbonic anhydrase 2 | 0.0222 | 2.55323972 | 0.30442619 |
CA3 | Carbonic anhydrase 3 | 0.0391 | 2.26309122 | 0.58876429 |
ATP synthase family | ||||
ATP5L | ATP synthase, H+ transporting, mitochondrial Fo complex subunit G | 0.000419 | 4.51769377 | 0.44282857 |
ATP23 | ATP23 metallopeptidase and ATP synthase assembly factor homolog | 0.000780 | 4.20573756 | 0.62625 |
ATP5G3 | ATP synthase, H+ transporting, mitochondrial Fo complex subunit C3 (subunit 9) | 0.00154 | 3.86838238 | 0.65084286 |
ATPAF1 | ATP synthase mitochondrial F1 complex assembly factor 1 | 0.00269 | 3.59573018 | 0.56412619 |
ATP5B | ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide | 0.0107 | 2.91564259 | 0.45252381 |
Tight junction claudins | ||||
CLDN18 | Claudin-18 | 0.0105 | 2.92789759 | 0.46640476 |
CLDN11 | Claudin-11 | 0.0190 | 2.63115902 | 0.64749762 |
CLDN5 | Claudin-5 | 0.0399 | 2.25235984 | 0.70879524 |
Others | ||||
APP | Amyloid beta precursor protein | 0.0144 | 2.77007349 | 0.41097857 |