Fig. 3
From: Tunneling nanotubes evoke pericyte/endothelial communication during normal and tumoral angiogenesis
Representative confocal microscopy images of pericyte TNTs in the developing human telencephalon at 22 wg. a Two microvessels (V) revealed by CD31+ endothelial cells and NG2+ activated pericytes (PC). b, c Bent (b, arrow) and straight (c, arrow) NG2+ TNT originate from pericytes (PC) associated with microvessels (V) lined by CD31+ endothelial cells. d A nearly undetectable, very thin and ultra-long NG2 TNT (arrow) connects a growing microvessel (V), escorted by a leading pericyte (arrowhead), to the recipient vessel (V); the encircled area corresponds to an overexposed laser confocal microscope setting. PC pericyte. Nuclear counterstaining TOPRO-3. Scale bars a–d 20 µm