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Table 1 Body and brain weights, blood pressure and heart rate in WKY and SHR rats

From: Blood–brain and blood–cerebrospinal fluid barrier permeability in spontaneously hypertensive rats

 

WKY (n = 10)

SHR (n = 10)

Weight

 Body (g)

401.0 ± 10.1

398.4 ± 2.6

 Brain (g)

2.12 ± 0.03

2.01 ± 0.01**

Blood pressure and heart rate

 Systolic (mmHg)

158.6 ± 2.1

190.5 ± 4.0****

 Diastolic (mmHg)

103.9 ± 2.3

145.7 ± 4.5****

 Heart rate (bpm)

386.1 ± 8.6

460.9 ± 7.0****

  1. Body weight did not differ between WKY and SHR, while brain wet weights were significantly lower in SHR. Both systolic and diastolic blood pressure, and heart rate were significantly elevated in SHR as compared to WKY. Values are mean ± SEM
  2. WKY Wistar Kyoto rat, SHR spontaneously hypertensive rat
  3. ** p ≤ 0.01 and **** p ≤ 0.0001 vs. WKY (unpaired Student’s t-test or Mann–Whitney U test)
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Fluids and Barriers of the CNS

ISSN: 2045-8118