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Fig. 6 | Fluids and Barriers of the CNS

Fig. 6

From: Accurate, strong, and stable reporting of choroid plexus epithelial cells in transgenic mice using a human transthyretin BAC

Fig. 6

TdTomato is expressed in pancreatic islets. A Native tdTomato fluorescence in wet mounts of pancreas from a 6-month old transgenic mouse (+) compared to a wild-type mouse (−), with a corresponding transmitted light image at right. Fluorescence was observed in round or ellipsoid patches, consistent with expression in pancreatic islets. B Immunofluorescence in an islet from a 3-week old transgenic mouse. Cells expressing tdTomato immunoreactivity (tdtom) are largely distinct from beta cells expressing insulin, although some insulin-positive cells appear to be weakly stained for tdTomato (arrows). C Native tdTomato fluorescence (tdtom*) occurs in the same regions exhibiting immunostaining for glucagon in an islet from an 8-day old mouse, suggesting an association with alpha cells, although certain tdTomato-expressing cells may lack anti-glucagon staining (arrowhead)

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