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Table 3 Reported studies of cerebrospinal fluid shunting in patients with glioblastoma

From: Challenges in cerebrospinal fluid shunting in patients with glioblastoma

Author, year

Frequency, n (%)

Type of CSF circulation disturbance

Shunt complication

Marquardt et al. 2002 [7]

12/351 malignant gliomas (3.4)

CH (n = 12)

Multiple surgeries due to multiloculated hydrocephalus (n = 1)

Inamasu et al. 2003 [8]

5/50 GBM (10)

CH (n = 5)

None reported

Roth et al. 2008 [11]

16/530 GBM (3)

CH (n = 16)

Infection (n = 6), shunt malfunction (n = 1), overdrainage and hemorrhage (n = 1)

Montano et al. 2011 [6]

11/124 GBM (8.9)

CH (n = 7), OH (n = 2), fluid in resection cavity (n = 2)

None reported

de la Fuente et al. 2014 [12]

41/2433 gliomas WHO grade II–IV (1.7)

CH (n = 41)

Meningitis (n = 5), subdural hematoma (n = 5), haemorrhage (n = 1), infection (n = 6)

Fischer et al. 2014 [9]

11/151 GBM (7.3)

CH (n = 11)

n.a.

Esquanazi et al., 2017 [27]

20/57 thalamic GBM (35)

OH (n = 20)

n.a.

Behling et al. 2017 [10]

13/229 GBM (5.7)

IH (n = 11), EH (n = 2)

n.a.

Castro et al. 2017 [13]

64/841 GBM (7.6)

CH (n = 42), OH (n = 22)

Infection (n = 10), catheter occlusion (n = 1), combined overdrainage, ventriculitis and haemorrhage (n = 1)

  1. GBM glioblastoma; CH communicating hydrocephalus; OH obstructive hydrocephalus; IH internal hydrocephalus; EH external hydrocephalus; CSF cerebrospinal fluid; n.a. not available