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Fig. 1 | Fluids and Barriers of the CNS

Fig. 1

From: Modeling and rescue of defective blood–brain barrier function of induced brain microvascular endothelial cells from childhood cerebral adrenoleukodystrophy patients

Fig. 1

iBMECs express the requisite endothelial, tight junction, and BBB markers. a Representative immunocytochemistry (WT1 and ccALD2). iBMECs from ccALD patients and WT controls express PECAM1, GLUT1, claudin-5, and occludin. No qualitative difference was observed between the WT and ccALD-iBMECs. b RT-PCR (all WT and ccALD lines). iBMECs from ccALD patients and WT controls express CDH5 (VE-cadherin) and SLC2A1 (GLUT1)

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Fluids and Barriers of the CNS

ISSN: 2045-8118