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Fig. 5 | Fluids and Barriers of the CNS

Fig. 5

From: Monoclonal antibody exposure in rat and cynomolgus monkey cerebrospinal fluid following systemic administration

Fig. 5

Representative serum and CSF concentration–time profiles of antibodies A and C from individual cynomolgus monkeys. a Represents antibody A at 100 mg/kg, b represents antibody A at 20 mg/kg, and c, d represent antibody C at 30 mg/kg in selective animals. Left y-axes denote serum concentrations in μg/mL (open circle). Right y-axes denote CSF concentration in ng/mL (open triangle)

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