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Fig. 4 | Fluids and Barriers of the CNS

Fig. 4

From: Monoclonal antibody exposure in rat and cynomolgus monkey cerebrospinal fluid following systemic administration

Fig. 4

Mean serum and CSF concentration–time profiles in adult male cynomolgus monkeys following single IV dose administration of antibody C (a) at 30 mg/kg (N = 6) or 100 mg/kg (N = 12) and following a single IV administration of antibody D (b) at 30 mg/kg. Left y-axes denote serum concentrations in μg/mL (open circle). Right y-axes denote CSF concentration in ng/mL (open triangle)

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Fluids and Barriers of the CNS

ISSN: 2045-8118