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Fig. 2 | Fluids and Barriers of the CNS

Fig. 2

From: Monoclonal antibody exposure in rat and cynomolgus monkey cerebrospinal fluid following systemic administration

Fig. 2

Serum and CNS tissue concentration–time profiles of antibody E in Brown Norway rats after a single intraperitoneal (IP) administration. Left y-axes denote serum concentration of antibody E in μg/mL (open circle). Right y-axes denote tissue concentrations of antibody E in ng/mL for CSF (open triangle, a) or ng/g of wet tissues for brain (open diamond, b) and spinal cord (open inverted triangle, c). Data for each individual animal are plotted separately

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