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Table 3 Comparison of cerebrospinal fluid absolute and normalized concentrations of common chemokines in control and post-hemorrhagic hydrocephalus subjects

From: Chemokine and cytokine levels in the lumbar cerebrospinal fluid of preterm infants with post-hemorrhagic hydrocephalus

 

Control

mean (SD)

PHH

mean (SD)

Mean difference

95% confidence interval

p value

XCL-1 (ng/ml)

0.6680 (0.0833)

0.5528 (0.1121)

− 0.1152

− 0.0224 to − 0.2079

0.0176

Normalized XCL-1

5.4E−5 (1.6E−5)

2.19E−5 (1.1E−5)

− 3.3E−5

− 1.76E−5 to − 4.8E−5

0.0002

CCL-2 (pg/ml)

9436 (5117)

9535 (5089)

99.45

− 4622 to 4821

n.s.

Normalized CCL-2

7.79E−4 (5.76E−4)

4.16E−4 (4.08E−4)

− 3.62E−4

− 8.47E−4 to 1.21E−4

n.s.

CCL-3 (pg/ml)

16.50 (11.02)

360.0 (327.7)

343.5

537.9–149.1

0.0018

Normalized CCL-3

0.015 (0.0092)

1.2E−5 (9.9E−6)

− 0.0146

− 0.00658 to − 0.0227

0.0014

CCL-19 (pg/ml)

28.46 (45.15)

410.8 (377.9)

382.4

591.8–173.0

0.0011

Normalized CCL-19

1.73E−6 (2.14E−6)

1.41E−5(2.1E−5)

1.23E−5

2.36E−5 to 9.96E−7

0.0345

CXCL-10 (pg/ml)

809.6 (776.6)

1480 (742.6)

670

1325–15.09

0.0454

Normalized CXCL-10

5.9E−5 (5.8E−5)

5.72E−5 (4.42E−5)

− 2.14E−6

4.32E-5 to − 4.75E-5

n.s.

CXCL-11 (pg/ml)

5.162 (10.68)

5.15 (4.58)

− 8.7E−3

7.869 to − 7.886

n.s.

Normalized CXCL-11

4.08E−7 (1.01E−6)

1.38E−7 (8.01E−8)

− 2.71E−7

4.39E−7 to − 9.80E−7

n.s.

CXCL-12 (ng/ml)

0.5187 (0.5528)

0.9930 (1.0002)

0.4743

1.052 to − 0.1033

n.s.

Normalized CXCL-12

4.5E−5 (5.3E−5)

1.4E−5 (9.6E−6)

− 3.01E−5

2.01E-5 to − 7.5E−5

n.s.

  1. SD standard deviation, PHH post-hemorrhagic hydrocephalus