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Fig. 1 | Fluids and Barriers of the CNS

Fig. 1

From: Dose escalation study of intravenous and intra-arterial N-acetylcysteine for the prevention of oto- and nephrotoxicity of cisplatin with a contrast-induced nephropathy model in patients with renal insufficiency

Fig. 1

Dosing algorithm for N-acetylcysteine to determine the maximum tolerated dose in adults with chronic kidney disease. The N-acetylcysteine maximum tolerated dose was defined as one dose level below the dose that produced grade 3 or 4 toxicity. MTD maximum tolerated dose

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Fluids and Barriers of the CNS

ISSN: 2045-8118