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Fig. 2 | Fluids and Barriers of the CNS

Fig. 2

From: Cerebrospinal fluid Aβ42, t-tau, and p-tau levels in the differential diagnosis of idiopathic normal-pressure hydrocephalus: a systematic review and meta-analysis

Fig. 2

Sensitivity analysis of CSF Aβ42 levels in iNPH compared to AD. Sensitivity analysis was performed by removing studies one by one and comparing the pooled estimate from the remaining studies with the pooled estimate from all studies. The X axis represents the pooled estimate and the Y axis represents the excluded studies. Analyses were conducted on the raw data and the pooled estimate was 0.33 (95% CI 0.00–0.65). The pooled estimate was different when the study of Seppala et al. [26], Miyajima et al. [24], Lim et al. [27], Pyykko et al. [21], Schirinzi et al. [28] were omitted separately. The pooled estimates (95% CI) were 0.37 (95% CI −0.05 to 0.79), 0.30 (95% CI −0.07 to 0.67), 0.22 (95% CI −0.07 to 0.51), 0.35 (95% CI −0.04 to 0.74), 0.25 (95% CI −0.07 to 0.56), respectively. This suggests that results of those between-groups analyses were not stable and reliable

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Fluids and Barriers of the CNS

ISSN: 2045-8118