Fig. 2

a Hematoxylin and eosin staining of a 1.6 cm biopsy of the frontal cortex that contained both grey and white matter. b Abundant TDP-43 pathology (arrows) was present, mostly in the form of thin neurites and varying shapes of inclusions, in both grey and white matter. Scale bar 100 µm. c There was moderate p62 (arrows) staining, mostly in thin neurites. Scale bar 100 µm