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Fig. 4 | Fluids and Barriers of the CNS

Fig. 4

From: Nrf2 signaling increases expression of ATP-binding cassette subfamily C mRNA transcripts at the blood–brain barrier following hypoxia-reoxygenation stress

Fig. 4

Involvement of Nrf2 in regulation of Abcc mRNA transcripts in rat brain microvessels following H/R. ChIP was performed on brain microvessels isolated from rats subjected to H/R (H = 6% O2, 1 h; R = 21% O2 for 10 min, 30 min or 1 h), Nx, Hx, or treated with sulforaphane for 3 h. Results are expressed as mean ± SD of three experiments, with each group consisting of pooled microvessels from three individual animals. *p < 0.05; **p < 0.01

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